This Article Free Full Text (Free PDF) Free References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ahmed, J. S. Articles by Seitzer, U. Search for Related Content PubMed PubMed Citation Articles by Ahmed, J. S. Articles by Seitzer, U. Social Bookmarking                   What's this?

Review: Innate immunity to tropical theileriosis

Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Borstel, Germany, jahmed{at}fz-borstel.de

Elizabeth J. Glass

Department of Genetics and Genomics, Roslin Institute and Royal (Dick) School of Veterinary Studies, Roslin Biocentre, Midlothian, UK

Diaeldin A. Salih

Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Borstel, Germany

Ulrike Seitzer

Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Borstel, Germany

The intracellular protozoan parasite Theileria annulata causes a severe, and often fatal, disease of pure and cross-bred cattle in tropical and subtropical countries. The present review refers to the importance of innate immunity as far as it is known to date in this infectious disease. Specifically, macrophages and the mediators produced by these cells are outlined. In addition, the latest findings concerning cattle breed differences in susceptibility to T. annulata infection in relation to macrophage activation are discussed.

Key Words: Theileria annulata • tropical theileriosis • innate immune response • resistant cattle breed

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?